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Gene Review

ORF3  -  hypothetical protein

Chlamydia psittaci

 
 
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Disease relevance of ORF3

  • We identified, by two-dimensional electrophoretic analysis and microsequencing, a protein of Chlamydia trachomatis elementary bodies which corresponds to the polypeptide (pgp3) encoded by open reading frame 3 (ORF3) [1].
  • Serum antibodies against recombinant C. psittaci protein (pgp3) encoded by orf3 were detected both in pigeons with C. psittaci infection and in a human patient with psittacosis [2].
 

High impact information on ORF3

References

  1. Humoral immune response to plasmid protein pgp3 in patients with Chlamydia trachomatis infection. Comanducci, M., Manetti, R., Bini, L., Santucci, A., Pallini, V., Cevenini, R., Sueur, J.M., Orfila, J., Ratti, G. Infect. Immun. (1994) [Pubmed]
  2. Comparative PCR-based restriction fragment length polymorphism analysis of the plasmid gene orf3 of Chlamydia trachomatis and Chlamydia psittaci. Storni, E., Donati, M., Marangoni, A., Accardo, S., Cevenini, R. FEMS Immunol. Med. Microbiol. (2006) [Pubmed]
 
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