Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

aliB - peptide ABC transporter substrate-binding...

Streptococcus pneumoniae R6

Hathaway, L.J. et al., Alloing, G. et al.

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Disease relevance of aliB

A homologue of aliB is found in the capsule region of nonencapsulated Streptococcus pneumoniae [1].
Group II strains also carried a 1,959-bp homologue of aliB (aliB-like ORF 2) in the capsule region, which was highly homologous to a sequence in the capsule region of Streptococcus mitis [1].

High impact information on aliB

Both genes (aliA and aliB) were cloned and shown to encode putative lipoproteins highly homologous to AmiA (close to 60% amino acid identity) [2].

Analytical, diagnostic and therapeutic context of aliB

Expression of aliB-like ORF 1 was detected by reverse transcription-PCR, and the corresponding RNA was visualized by Northern blotting [1].

References

A homologue of aliB is found in the capsule region of nonencapsulated Streptococcus pneumoniae. Hathaway, L.J., Stutzmann Meier, P., Bättig, P., Aebi, S., Mühlemann, K. J. Bacteriol. (2004) [Pubmed]
Three highly homologous membrane-bound lipoproteins participate in oligopeptide transport by the Ami system of the gram-positive Streptococcus pneumoniae. Alloing, G., de Philip, P., Claverys, J.P. J. Mol. Biol. (1994) [Pubmed]

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