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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

TGFBRAP1  -  transforming growth factor, beta receptor...

Homo sapiens

Synonyms: TGF-beta receptor-associated protein 1, TRAP-1, TRAP1, Transforming growth factor-beta receptor-associated protein 1
 
 
 
 
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High impact information on TGFBRAP1

  • The partial TRAP-1 protein that specifically binds these mutationally and ligand-activated forms of TbetaR-I can inhibit signaling by the native receptor after stimulation with TGFbeta or by the constitutively activated receptor mutation, as measured by a TGFbeta-dependent reporter gene [1].

References

  1. A novel protein distinguishes between quiescent and activated forms of the type I transforming growth factor beta receptor. Charng, M.J., Zhang, D., Kinnunen, P., Schneider, M.D. J. Biol. Chem. (1998) [Pubmed]
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