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Gene Review:

rnhB - ribonuclease HII, degrades RNA of DNA-RNA...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK0182, JW0178

Itaya, M. et al., Zhang, Y.B. et al., Muroya, A. et al.

Itaya, Omori, Kanaya, Crouch, Tanaka, Kondo,

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Disease relevance of rnhB

This observation indicated that in B. subtilis both the rnhB and rnhC products are involved in certain essential cellular processes that are different from those suggested by E. coli rnh mutation studies [1].
The rnhB gene encoding RNase HII of Streptococcus pneumoniae and evidence of conserved motifs in eucaryotic genes [2].
Importance of an N-terminal extension in ribonuclease HII from Bacillus stearothermophilus for substrate binding [3].

References

Isolation of RNase H genes that are essential for growth of Bacillus subtilis 168. Itaya, M., Omori, A., Kanaya, S., Crouch, R.J., Tanaka, T., Kondo, K. J. Bacteriol. (1999) [Pubmed]
The rnhB gene encoding RNase HII of Streptococcus pneumoniae and evidence of conserved motifs in eucaryotic genes. Zhang, Y.B., Ayalew, S., Lacks, S.A. J. Bacteriol. (1997) [Pubmed]
Importance of an N-terminal extension in ribonuclease HII from Bacillus stearothermophilus for substrate binding. Muroya, A., Nakano, R., Ohtani, N., Haruki, M., Morikawa, M., Kanaya, S. J. Biosci. Bioeng. (2002) [Pubmed]

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