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Gene Review

cobB  -  deacetylase of acs and cheY, chemotaxis...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK1106, JW1106, npdA, ycfY
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Disease relevance of cobB


High impact information on cobB

  • Recombinant E. coli cobT and cobB proteins each showed a weak NAD-dependent mono-ADP-ribosyltransferase activity using 5, 6-dimethylbenzimidazole as a substrate [2].

Analytical, diagnostic and therapeutic context of cobB

  • Isothermal titration calorimetry studies were used to compare the affinity of cobB for a variety of cognate and non-cognate acetyl-lysine-bearing peptides revealing an exothermic reaction with relatively little discrimination between substrates [1].


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