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Gene Review

paaX  -  transcriptional repressor of phenylacetic...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK1396, JW1394, ydbY
 
 
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Disease relevance of paaX

  • Finally, the inactivation of both paaX gene copies of Pseudomonas sp. strain Y2 leads to a higher level of transcription from the P(styA) promoter, while heterologous expression of the PaaX1 in E. coli greatly decreases transcription from the P(styA) promoter [1].
 

High impact information on paaX

  • Three promoters, Pz, Pa, and Px, driven the expression of genes paaZ, paaABCDEFGHIJK, and paaX, respectively, have been identified [2].

References

  1. Coregulation by phenylacetyl-coenzyme A-responsive PaaX integrates control of the upper and lower pathways for catabolism of styrene by Pseudomonas sp. strain Y2. del Peso-Santos, T., Bartolomé-Martín, D., Fernández, C., Alonso, S., García, J.L., Díaz, E., Shingler, V., Perera, J. J. Bacteriol. (2006) [Pubmed]
  2. Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway. Ferrández, A., Miñambres, B., García, B., Olivera, E.R., Luengo, J.M., García, J.L., Díaz, E. J. Biol. Chem. (1998) [Pubmed]
 
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