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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

fbaB  -  fructose-bisphosphate aldolase class I

Escherichia coli str. K-12 substr. MG1655

 
 
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Disease relevance of fbaB

  • This gene sequence has previously been identified as encoding an E. coli dehydrin in the GenBanktrade mark database [gene dhnA; entry code U73760; Close and Choi (1996) Submission to GenBanktrade mark] [1].
  • Thermostable variants of the Class II fructose bisphosphate aldolase have been isolated following four rounds of directed evolution using DNA shuffling of the fda genes from Escherichia coli and Edwardsiella ictaluri [2].

References

  1. The dhnA gene of Escherichia coli encodes a class I fructose bisphosphate aldolase. Thomson, G.J., Howlett, G.J., Ashcroft, A.E., Berry, A. Biochem. J. (1998) [Pubmed]
  2. A thermostable variant of fructose bisphosphate aldolase constructed by directed evolution also shows increased stability in organic solvents. Hao, J., Berry, A. Protein Eng. Des. Sel. (2004) [Pubmed]
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