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Gene Review:

bacA - undecaprenyl pyrophosphate phosphatase

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3047, JW3029, uppP

El Ghachi, M. et al., El Ghachi, M. et al.

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Disease relevance of bacA

Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli [1].

High impact information on bacA

The analysis of its catalytic properties clearly demonstrated that the purified BacA protein exhibited undecaprenyl pyrophosphate phosphatase activity but not undecaprenol phosphokinase activity [2].
The level of undecaprenyl pyrophosphate phosphatase was increased by 280-fold in cells carrying bacA on a multicopy expression plasmid [2].

References

Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli. El Ghachi, M., Derbise, A., Bouhss, A., Mengin-Lecreulx, D. J. Biol. Chem. (2005) [Pubmed]
The bacA gene of Escherichia coli encodes an undecaprenyl pyrophosphate phosphatase activity. El Ghachi, M., Bouhss, A., Blanot, D., Mengin-Lecreulx, D. J. Biol. Chem. (2004) [Pubmed]

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