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Gene Review

MED20  -  mediator complex subunit 20

Homo sapiens

Synonyms: DKFZp586D2223, Mediator complex subunit 20, Mediator of RNA polymerase II transcription subunit 20, PRO0213, TRF-proximal protein homolog, ...
 
 
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High impact information on TRFP

  • In addition, we show that hIntersex assembles into a subcomplex with Mediator subunits p28b and TRFP [1].
  • Thus, hTRFP may regulate transcription of class II genes through association with the RNA polymerase II-SRB complex [2].

References

  1. A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex. Sato, S., Tomomori-Sato, C., Banks, C.A., Parmely, T.J., Sorokina, I., Brower, C.S., Conaway, R.C., Conaway, J.W. J. Biol. Chem. (2003) [Pubmed]
  2. The human homologue of Drosophila TRF-proximal protein is associated with an RNA polymerase II-SRB complex. Xiao, H., Tao, Y., Roeder, R.G. J. Biol. Chem. (1999) [Pubmed]
 
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