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Gene Review:

iap - invasion associated secreted endopeptidase

Listeria monocytogenes EGD-e

Mukhopadhyay, A. et al., Machata, S. et al.

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Disease relevance of iap

To develop a single, rapid and sensitive PCR based test for simultaneous detection of both the organisms, fliCh(7) and iap gene specific primers were used respectively for E. coli 0157:H7 and L. monocytogenes [1].

High impact information on iap

To determine the gene products required for the smooth-rough transition, we created mutants lacking the individual iap and murA genes as well as a Deltaiap DeltamurA double mutant [2].

References

Novel multiplex PCR approaches for the simultaneous detection of human pathogens: Escherichia coli 0157:H7 and Listeria monocytogenes. Mukhopadhyay, A., K Mukhopadhyay, U. J. Microbiol. Methods (2007) [Pubmed]
Simultaneous deficiency of both MurA and p60 proteins generates a rough phenotype in Listeria monocytogenes. Machata, S., Hain, T., Rohde, M., Chakraborty, T. J. Bacteriol. (2005) [Pubmed]

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