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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Platybasia


High impact information on Platybasia


Gene context of Platybasia

  • The symptoms of the basilar impression are probably caused by compression of the vessels of the lower cerebellar region and the brainstem as well as by disturbances of the CSF circulation [7].
  • (3) The most appropriate operative procedure must be selected: stable platybasia with a nervous compression by Chiari is cured only by posterior decompression; odontoid instability is cured by reduction and posterior fixation, using hooks and autologous bone grafts on the posterior arches of C-1 and C-2 [8].
  • Basilar impression associated with this case may be considered a pure coincidence, but rare cases of basilar impression and NF1 have been described [9].


  1. Marfan's syndrome, ventricular septal defect and basilar impression in one patient. Yajnik, V.H., Kshatriya, P.K., Vaidya, M.H., Vassa, N.T. Journal of the Indian Medical Association. (1975) [Pubmed]
  2. Homonucleotide expansion and contraction mutations of PAX2 and inclusion of Chiari 1 malformation as part of renal-coloboma syndrome. Schimmenti, L.A., Shim, H.H., Wirtschafter, J.D., Panzarino, V.A., Kashtan, C.E., Kirkpatrick, S.J., Wargowski, D.S., France, T.D., Michel, E., Dobyns, W.B. Hum. Mutat. (1999) [Pubmed]
  3. Pediatric transoral surgery: indications, complications, and long-term outcome. Tuite, G.F., Veres, R., Crockard, H.A., Sell, D. J. Neurosurg. (1996) [Pubmed]
  4. Stroke due to a fusiform aneurysm of the cervical vertebral artery: case report. Suzuki, S., Inoue, T., Haga, S., Nishio, S., Kono, S., Mizushima, A., Fukui, M. Neuroradiology. (1998) [Pubmed]
  5. Cervicovertebral anomalies and basilar impression in Goldenhar syndrome. Gosain, A.K., McCarthy, J.G., Pinto, R.S. Plast. Reconstr. Surg. (1994) [Pubmed]
  6. A case of basilar impression complicated with left frontal meningioma. Asamoto, S., Nestler, U., Shulz, C., Böker, D.K. No shinkei geka. Neurological surgery. (2003) [Pubmed]
  7. Basilar impression. A differential diagnosis of Menier'es disease. Elies, W., Plester, D. Archives of otolaryngology (Chicago, Ill. : 1960) (1980) [Pubmed]
  8. Management of craniocervical junction dislocation. Chirossel, J.P., Passagia, J.G., Gay, E., Palombi, O. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. (2000) [Pubmed]
  9. Neurofibromatosis, stroke and basilar impression. Case report. Piovesan, E.J., Scola, R.H., Werneck, L.C., Zétola, V.H., Nóvak, E.M., Iwamoto, F.M., Piovesan, L.M. Arquivos de neuro-psiquiatria. (1999) [Pubmed]
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