Gene Review:
GHS - Goldenhar syndrome
Homo sapiens
Kohlhase,
Taschner,
Burfeind,
Pasche,
Newman,
Blanck,
Breuning,
ten Kate,
Maaswinkel-Mooy,
Mitulla,
Seidel,
Kirkpatrick,
Pauli,
Wargowski,
Devriendt,
Proesmans,
Gabrielli,
Coppa,
Wesby-van Swaay,
Trembath,
Schinzel,
Reardon,
Seemanova,
Engel,
Stanojević,
Stipoljev,
Koprcina,
Kurjak,
Correa-Silva,
Nascif,
Lengyel,
Miller,
Strömland,
Ventura,
Johansson,
Bandim,
Gillberg,
- Identification, characterization, and biological activity of specific receptors for natural (ghrelin) and synthetic growth hormone secretagogues and analogs in human breast carcinomas and cell lines. Cassoni, P., Papotti, M., Ghè, C., Catapano, F., Sapino, A., Graziani, A., Deghenghi, R., Reissmann, T., Ghigo, E., Muccioli, G. J. Clin. Endocrinol. Metab. (2001)
- Ghrelin promotes slow-wave sleep in humans. Weikel, J.C., Wichniak, A., Ising, M., Brunner, H., Friess, E., Held, K., Mathias, S., Schmid, D.A., Uhr, M., Steiger, A. Am. J. Physiol. Endocrinol. Metab. (2003)
- Alprazolam, a benzodiazepine, blunts but does not abolish the ACTH and cortisol response to hexarelin, a GHRP, in obese patients. Grottoli, S., Arvat, E., Gauna, C., Maccagno, B., Ramunni, J., Giordano, R., Maccario, M., Deghenghi, R., Ghigo, E. Int. J. Obes. Relat. Metab. Disord. (2000)
- Gordon Holmes spinocerebellar ataxia: a gonadotrophin deficiency syndrome resistant to treatment with pulsatile gonadotrophin-releasing hormone. Quinton, R., Barnett, P., Coskeran, P., Bouloux, P.M. Clin. Endocrinol. (Oxf) (1999)
- Estimating the prevalence of mental and somatic disorders in the community: aims and methods of the German National Health Interview and Examination Survey. Jacobi, F., Wittchen, H.U., Hölting, C., Sommer, S., Lieb, R., Höfler, M., Pfister, H. International journal of methods in psychiatric research. (2002)
- Hopelessness in community-residing aged persons: a viable construct? Hayslip, B., Lopez, F.G., Nation, P. Journal of personality assessment. (1991)
- Central and peripheral activities of ghrelin, a ligand of the growth hormone secretagogue receptor. Bona, G., Bellone, S. Panminerva medica. (2003)
- The safety needle switchover, part 2 of 2. Steed, C., Baker, M. Nursing management. (2002)
- Goldenhar syndrome and autistic behaviour. Landgren, M., Gillberg, C., Strömland, K. Developmental medicine and child neurology. (1992)
- Development of growth hormone secretagogues. Smith, R.G. Endocr. Rev. (2005)
- Molecular analysis of SALL1 mutations in Townes-Brocks syndrome. Kohlhase, J., Taschner, P.E., Burfeind, P., Pasche, B., Newman, B., Blanck, C., Breuning, M.H., ten Kate, L.P., Maaswinkel-Mooy, P., Mitulla, B., Seidel, J., Kirkpatrick, S.J., Pauli, R.M., Wargowski, D.S., Devriendt, K., Proesmans, W., Gabrielli, O., Coppa, G.V., Wesby-van Swaay, E., Trembath, R.C., Schinzel, A.A., Reardon, W., Seemanova, E., Engel, W. Am. J. Hum. Genet. (1999)
- Effects of ghrelin and synthetic GH secretagogues on the cardiovascular system. Cao, J.M., Ong, H., Chen, C. Trends Endocrinol. Metab. (2006)
- Cyclical Cushing's syndrome in a patient with a bronchial neuroendocrine tumor (typical carcinoid) expressing ghrelin and growth hormone secretagogue receptors. Arnaldi, G., Mancini, T., Kola, B., Appolloni, G., Freddi, S., Concettoni, C., Bearzi, I., Masini, A., Boscaro, M., Mantero, F. J. Clin. Endocrinol. Metab. (2003)
- Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans. Broglio, F., Arvat, E., Benso, A., Gottero, C., Muccioli, G., Papotti, M., van der Lely, A.J., Deghenghi, R., Ghigo, E. J. Clin. Endocrinol. Metab. (2001)
- Effects of alprazolam, a benzodiazepine, on the ACTH-, GH- and PRL-releasing activity of hexarelin, a synthetic peptidyl GH secretagogue (GHS), in patients with simple obesity and in patients with Cushing's disease. Grottoli, S., Arvat, E., Gauna, C., Maccagno, B., Ramunni, J., Giordano, R., Maccario, M., Deghenghi, R., Ghigo, E. Pituitary (1999)
- Ghrelin, hypothalamus-pituitary-adrenal (HPA) axis and Cushing's syndrome. Giordano, R., Picu, A., Broglio, F., Bonelli, L., Baldi, M., Berardelli, R., Ghigo, E., Arvat, E. Pituitary (2004)
- Autism associated with conditions characterized by developmental errors in early embryogenesis: a mini review. Miller, M.T., Strömland, K., Ventura, L., Johansson, M., Bandim, J.M., Gillberg, C. Int. J. Dev. Neurosci. (2005)
- Goldenhar syndrome, anterior encephalocele, and aqueductal stenosis following fetal primidone exposure. Gustavson, E.E., Chen, H. Teratology (1985)
- [125I-His(9)]-ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: up-regulation of receptors with athersclerosis. Katugampola, S.D., Pallikaros, Z., Davenport, A.P. Br. J. Pharmacol. (2001)
- Ghrelin: more than a natural GH secretagogue and/or an orexigenic factor. Ghigo, E., Broglio, F., Arvat, E., Maccario, M., Papotti, M., Muccioli, G. Clin. Endocrinol. (Oxf) (2005)
- Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity. Muccioli, G., Tschöp, M., Papotti, M., Deghenghi, R., Heiman, M., Ghigo, E. Eur. J. Pharmacol. (2002)
- Natural (ghrelin) and synthetic (hexarelin) GH secretagogues stimulate H9c2 cardiomyocyte cell proliferation. Pettersson, I., Muccioli, G., Granata, R., Deghenghi, R., Ghigo, E., Ohlsson, C., Isgaard, J. J. Endocrinol. (2002)
- Statistical evaluation of an acute dermal toxicity test using the dermal fixed dose procedure. Stallard, N., Whitehead, A., Indans, I. Human & experimental toxicology. (2004)
- Growth hormone secretagogue binding sites in peripheral human tissues. Papotti, M., Ghè, C., Cassoni, P., Catapano, F., Deghenghi, R., Ghigo, E., Muccioli, G. J. Clin. Endocrinol. Metab. (2000)
- Discontinuation of growth hormone (GH) treatment: metabolic effects in GH-deficient and GH-sufficient adolescent patients compared with control subjects. Swedish Study Group for Growth Hormone Treatment in Children. Johannsson, G., Albertsson-Wikland, K., Bengtsson, B.A. J. Clin. Endocrinol. Metab. (1999)
- d-Lys-GHRP-6 does not modify the endocrine response to acylated ghrelin or hexarelin in humans. Benso, A., Prodam, F., Lucatello, B., Gramaglia, E., Riganti, F., Schneider, H., van der Lely, A.J., Muccioli, G., Ghigo, E., Broglio, F. Neuropeptides (2007)
- Testosterone inhibition of growth hormone release stimulated by a growth hormone secretagogue. Studies in the rat and dog. Rigamonti, A.E., Cella, S.G., Giordani, C., Bonomo, S.M., Giunta, M., Sartorio, A., Muller, E. Neuroendocrinology (2006)
- Decreased GH secretion and enhanced ACTH and cortisol release after ghrelin administration in Cushing's disease: Comparison with GH-releasing peptide-6 (GHRP-6) and GHRH. Correa-Silva, S.R., Nascif, S.O., Lengyel, A.M. Pituitary (2006)
- The GH-releasing effect of ghrelin, a natural GH secretagogue, is only blunted by the infusion of exogenous somatostatin in humans. Di Vito, L., Broglio, F., Benso, A., Gottero, C., Prodam, F., Papotti, M., Muccioli, G., Dieguez, C., Casanueva, F.F., Deghenghi, R., Ghigo, E., Arvat, E. Clin. Endocrinol. (Oxf) (2002)
- Oculo-auriculo-vertebral (Goldenhar) spectrum associated with pericentric inversion 9: coincidental findings or etiologic factor? Stanojević, M., Stipoljev, F., Koprcina, B., Kurjak, A. J. Craniofac. Genet. Dev. Biol. (2000)
- GH-related and extra-endocrine actions of GH secretagogues in aging. Muller, E.E., Rigamonti, A.E., Colonna, V.d.e. .G., Locatelli, V., Berti, F., Cella, S.G. Neurobiol. Aging (2002)
- Targeting the ghrelin receptor: orally active GHS and cortistatin analogs. Deghenghi, R., Broglio, F., Papotti, M., Muccioli, G., Ghigo, E. Endocrine (2003)
- Endocrine and non-endocrine activities of growth hormone secretagogues in humans. Ghigo, E., Arvat, E., Broglio, F., Giordano, R., Gianotti, L., Muccioli, G., Papotti, M., Graziani, A., Bisi, G., Deghenghi, R., Camanni, F. Horm. Res. (1999)
- Presence of cortistatin in the human pancreas. Papotti, M., Tarabra, E., Allia, E., Bozzalla-Cassione, F., Broglio, F., Deghenghi, R., Ghigo, E., Muccioli, G. J. Endocrinol. Invest. (2003)
- Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues. Feighner, S.D., Howard, A.D., Prendergast, K., Palyha, O.C., Hreniuk, D.L., Nargund, R., Underwood, D., Tata, J.R., Dean, D.C., Tan, C.P., McKee, K.K., Woods, J.W., Patchett, A.A., Smith, R.G., Van der Ploeg, L.H. Mol. Endocrinol. (1998)
- Hexarelin decreases slow-wave sleep and stimulates the secretion of GH, ACTH, cortisol and prolactin during sleep in healthy volunteers. Frieboes, R.M., Antonijevic, I.A., Held, K., Murck, H., Pollmächer, T., Uhr, M., Steiger, A. Psychoneuroendocrinology (2004)
- Serum ghrelin levels are suppressed in hypopituitary patients following insulin-induced hypoglycaemia irrespective of GH status. Ryber, L., Obrink, K., Houe, N., Frystyk, J., Jørgensen, J.O. Clin. Endocrinol. (Oxf) (2006)
- Acute cardiovascular and hormonal effects of GH and hexarelin, a synthetic GH-releasing peptide, in humans. Bisi, G., Podio, V., Valetto, M.R., Broglio, F., Bertuccio, G., Del Rio, G., Arvat, E., Boghen, M.F., Deghenghi, R., Muccioli, G., Ong, H., Ghigo, E. J. Endocrinol. Invest. (1999)