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MeSH Review

Chronobiology Disorders

 
 
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High impact information on Chronobiology Disorders

  • We examined the relationship between the neuropathology of Alzheimer disease, as modeled by an animal system, and circadian dysregulation by grafting genetically transformed cells that overexpress beta/A4 amyloid into the suprachiasmatic nuclei of adult rats [1].
  • Persistence of hyperactivity or circadian dysregulation in bipolar patients treated with lithium appears to predict rapid relapse once medication is discontinued [2].

References

  1. Disruption of circadian regulation by brain grafts that overexpress Alzheimer beta/A4 amyloid. Tate, B., Aboody-Guterman, K.S., Morris, A.M., Walcott, E.C., Majocha, R.E., Marotta, C.A. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  2. Actigraphy and motion analysis: new tools for psychiatry. Teicher, M.H. Harvard review of psychiatry. (1995) [Pubmed]
 
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