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MeSH Review

Chromosomes, Human, Pair 17

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Disease relevance of Chromosomes, Human, Pair 17


High impact information on Chromosomes, Human, Pair 17

  • The Tme locus is absent in two chromosome-17 deletion mutants, Thp and the tLub2, and its position has been localized using these deletions to a 1-cM region [2].


  1. The achondroplasia gene is not linked to the locus for neurofibromatosis 1 on chromosome 17. Pulst, S.M., Graham, J.M., Fain, P., Barker, D., Pribyl, T., Korenberg, J.R. Hum. Genet. (1990) [Pubmed]
  2. The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus. Barlow, D.P., Stöger, R., Herrmann, B.G., Saito, K., Schweifer, N. Nature (1991) [Pubmed]
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