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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Role of gamma interferon and interleukin-4 in host defense against the human filarial parasite Brugia malayi.

We have investigated the roles of gamma interferon ( IFN-gamma) and interleukin-4 ( IL-4) in host defense against Brugia malayi. Our data suggest that the lack of either IFN-gamma or IL-4 prolongs the time required to achieve sterile immunity, suggesting that both canonical type 1 and type 2 responses are involved in the clearance of infection.[1]

References

  1. Role of gamma interferon and interleukin-4 in host defense against the human filarial parasite Brugia malayi. Babu, S., Ganley, L.M., Klei, T.R., Shultz, L.D., Rajan, T.V. Infect. Immun. (2000) [Pubmed]
 
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