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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Decreased cerebrospinal fluid levels of beta-phenylethylamine in patients with Rett syndrome.

To clarify the mechanism of brain impairment in Rett syndrome, we measured the cerebrospinal fluid levels of beta-phenylethylamine (PEA) in 17 patients with Rett syndrome. Findings were compared with those obtained in age-matched controls and diseased controls. The cerebrospinal fluid level of PEA was significantly lower in patients with Rett syndrome than in the controls (31% of control values). The alteration in the cerebrospinal fluid level of PEA may reflect dopamine system impairment in Rett syndrome.[1]

References

  1. Decreased cerebrospinal fluid levels of beta-phenylethylamine in patients with Rett syndrome. Satoi, M., Matsuishi, T., Yamada, S., Yamashita, Y., Ohtaki, E., Mori, K., Riikonen, R., Kato, H., Percy, A.K. Ann. Neurol. (2000) [Pubmed]
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