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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Cytotoxic triterpene acids from the Peruvian medicinal plant Polylepis racemosa.

Cytotoxicity-guided fractionation of the bark and stem extract of Polylepis racemosa led to the identification of ursolic acid, pomolic acid, 3-O-acetylpomolic acid, and 2-oxopomolic acid. Pomolic acid was the most cytotoxic component, and was specific for M-14 melanoma and ME180 cervical carcinoma, with GI50 values of 6.9 and 8.3 micrograms/mL respectively.[1]

References

  1. Cytotoxic triterpene acids from the Peruvian medicinal plant Polylepis racemosa. Neto, C.C., Vaisberg, A.J., Zhou, B.N., Kingston, D.G., Hammond, G.B. Planta Med. (2000) [Pubmed]
 
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