Gene Review:
Icosl - icos ligand
Mus musculus
Synonyms:
AU044799, B7 homolog 2, B7-H2, B7-like protein Gl50, B7-related protein 1, ...
- Amelioration of collagen-induced arthritis by blockade of inducible costimulator-B7 homologous protein costimulation. Iwai, H., Kozono, Y., Hirose, S., Akiba, H., Yagita, H., Okumura, K., Kohsaka, H., Miyasaka, N., Azuma, M. J. Immunol. (2002)
- Renal tubular epithelial expression of the costimulatory molecule B7RP-1 (inducible costimulator ligand). Wahl, P., Schoop, R., Bilic, G., Neuweiler, J., Le Hir, M., Yoshinaga, S.K., Wüthrich, R.P. J. Am. Soc. Nephrol. (2002)
- Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Akbari, O., Freeman, G.J., Meyer, E.H., Greenfield, E.A., Chang, T.T., Sharpe, A.H., Berry, G., DeKruyff, R.H., Umetsu, D.T. Nat. Med. (2002)
- ICOS-B7 homologous protein interactions are necessary for mercury-induced autoimmunity. Zheng, Y., Jost, M., Gaughan, J.P., Class, R., Coyle, A.J., Monestier, M. J. Immunol. (2005)
- Bacterial probiotic modulation of dendritic cells. Drakes, M., Blanchard, T., Czinn, S. Infect. Immun. (2004)
- ICOS is essential for effective T-helper-cell responses. Tafuri, A., Shahinian, A., Bladt, F., Yoshinaga, S.K., Jordana, M., Wakeham, A., Boucher, L.M., Bouchard, D., Chan, V.S., Duncan, G., Odermatt, B., Ho, A., Itie, A., Horan, T., Whoriskey, J.S., Pawson, T., Penninger, J.M., Ohashi, P.S., Mak, T.W. Nature (2001)
- ICOS co-stimulatory receptor is essential for T-cell activation and function. Dong, C., Juedes, A.E., Temann, U.A., Shresta, S., Allison, J.P., Ruddle, N.H., Flavell, R.A. Nature (2001)
- Mechanism-based competitive inhibitors of glyoxalase I: intracellular delivery, in vitro antitumor activities, and stabilities in human serum and mouse serum. Kavarana, M.J., Kovaleva, E.G., Creighton, D.J., Wollman, M.B., Eiseman, J.L. J. Med. Chem. (1999)
- 4-Substituted 4-hydroxycyclohexa-2,5-dien-1-ones with selective activities against colon and renal cancer cell lines. Wells, G., Berry, J.M., Bradshaw, T.D., Burger, A.M., Seaton, A., Wang, B., Westwell, A.D., Stevens, M.F. J. Med. Chem. (2003)
- Cytotoxic triterpene acids from the Peruvian medicinal plant Polylepis racemosa. Neto, C.C., Vaisberg, A.J., Zhou, B.N., Kingston, D.G., Hammond, G.B. Planta Med. (2000)
- Induction of growth inhibition and G1 arrest in human cancer cell lines by relatively low-toxic diamantane derivatives. Wang, J.J., Huang, K.T., Chern, Y.T. Anticancer Drugs (2004)
- Antagonism between MyD88- and TRIF-dependent signals in B7RP-1 up-regulation. Zhou, Z., Hoebe, K., Du, X., Jiang, Z., Shamel, L., Beutler, B. Eur. J. Immunol. (2005)
- Interaction of B7RP-1 with ICOS negatively regulates antigen presentation by B cells. Wahl, P., Schoop, R., Horan, T.P., Yoshinaga, S.K., Wüthrich, R.P. Inflammation (2003)
- Constitutive expression of the B7h ligand for inducible costimulator on naive B cells is extinguished after activation by distinct B cell receptor and interleukin 4 receptor-mediated pathways and can be rescued by CD40 signaling. Liang, L., Porter, E.M., Sha, W.C. J. Exp. Med. (2002)
- The role of inducible co-stimulator (ICOS)/B7-related protein-1 (B7RP-1) interaction in the functional development of Peyer's patches. Iiyama, R., Kanai, T., Uraushihara, K., Totsuka, T., Nakamura, T., Miyata, T., Yagita, H., Kushi, A., Suzuki, K., Tezuka, K., Watanabe, M. Immunol. Lett. (2003)
- B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha. Swallow, M.M., Wallin, J.J., Sha, W.C. Immunity (1999)
- Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses. Mak, T.W., Shahinian, A., Yoshinaga, S.K., Wakeham, A., Boucher, L.M., Pintilie, M., Duncan, G., Gajewska, B.U., Gronski, M., Eriksson, U., Odermatt, B., Ho, A., Bouchard, D., Whorisky, J.S., Jordana, M., Ohashi, P.S., Pawson, T., Bladt, F., Tafuri, A. Nat. Immunol. (2003)
- The ICOS-ligand B7-H2, expressed on human type II alveolar epithelial cells, plays a role in the pulmonary host defense system. Qian, X., Agematsu, K., Freeman, G.J., Tagawa, Y., Sugane, K., Hayashi, T. Eur. J. Immunol. (2006)
- Inducible costimulatory molecule-B7-related protein 1 interactions are important for the clonal expansion and B cell helper functions of naive, Th1, and Th2 T cells. Smith, K.M., Brewer, J.M., Webb, P., Coyle, A.J., Gutierrez-Ramos, C., Garside, P. J. Immunol. (2003)
- Antitumor mechanism of evodiamine, a constituent from Chinese herb Evodiae fructus, in human multiple-drug resistant breast cancer NCI/ADR-RES cells in vitro and in vivo. Liao, C.H., Pan, S.L., Guh, J.H., Chang, Y.L., Pai, H.C., Lin, C.H., Teng, C.M. Carcinogenesis (2005)
- Antitumor agents. 174. 2',3',4',5,6,7-Substituted 2-phenyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization. Chen, K., Kuo, S.C., Hsieh, M.C., Mauger, A., Lin, C.M., Hamel, E., Lee, K.H. J. Med. Chem. (1997)
- A new method for rapidly generating inhibitors of glyoxalase I inside tumor cells using S-(N-aryl-N-hydroxycarbamoyl)ethylsulfoxides. Hamilton, D.S., Kavarana, M.J., Sharkey, E.M., Eiseman, J.L., Creighton, D.J. J. Med. Chem. (1999)
- Biological mechanisms of action of novel C-10 non-acetal trioxane dimers in prostate cancer cell lines. Alagbala, A.A., McRiner, A.J., Borstnik, K., Labonte, T., Chang, W., D'Angelo, J.G., Posner, G.H., Foster, B.A. J. Med. Chem. (2006)
- Role of the B7RP-1/ICOS pathway in renal tubular epithelial antigen presentation to CD4+ Th1 and Th2 cells. Wahl, P., Wüthrich, R.P. Nephron Exp. Nephrol. (2004)
- Disruption of the ICOS-B7RP-1 costimulatory pathway leads to enhanced hepatic immunopathology and increased gamma interferon production by CD4 T cells in murine schistosomiasis. Rutitzky, L.I., Ozkaynak, E., Rottman, J.B., Stadecker, M.J. Infect. Immun. (2003)
- Chlamydia Infection Induces ICOS Ligand-Expressing and IL-10-Producing Dendritic Cells That Can Inhibit Airway Inflammation and Mucus Overproduction Elicited by Allergen Challenge in BALB/c Mice. Han, X., Wang, S., Fan, Y., Yang, J., Jiao, L., Qiu, H., Yang, X. J. Immunol. (2006)
- Comparable in vivo efficacy of CD28/B7, ICOS/GL50, and ICOS/GL50B costimulatory pathways in murine tumor models: IFNgamma-dependent enhancement of CTL priming, effector functions, and tumor specific memory CTL. Zuberek, K., Ling, V., Wu, P., Ma, H.L., Leonard, J.P., Collins, M., Dunussi-Joannopoulos, K. Cell. Immunol. (2003)
- The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity. Harada, H., Salama, A.D., Sho, M., Izawa, A., Sandner, S.E., Ito, T., Akiba, H., Yagita, H., Sharpe, A.H., Freeman, G.J., Sayegh, M.H. J. Clin. Invest. (2003)
- The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo. Akiba, H., Takeda, K., Kojima, Y., Usui, Y., Harada, N., Yamazaki, T., Ma, J., Tezuka, K., Yagita, H., Okumura, K. J. Immunol. (2005)
- Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand. Mages, H.W., Hutloff, A., Heuck, C., Büchner, K., Himmelbauer, H., Oliveri, F., Kroczek, R.A. Eur. J. Immunol. (2000)