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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle.

Cyclin-dependent kinases are the key regulators of cell-cycle transitions. In mammalian cells, Cdk2, Cdk4, Cdk6 and associated cyclins control the G(1) to S phase transition. Because proper regulation of this transition is critical for an organism's survival, these protein kinases are exquisitely regulated at different mechanistic levels and in response to a large variety of intrinsic and extrinsic signals.[1]

References

  1. Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle. Ekholm, S.V., Reed, S.I. Curr. Opin. Cell Biol. (2000) [Pubmed]
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