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Michel, U. et al.

Michel, Zobotke, Mäder, Nau,

Regulation of matrix metalloproteinase expression in endothelial cells by heat-inactivated Streptococcus pneumoniae.

Matrix metalloproteinases (MMPs) may contribute to an impaired endothelial layer in several diseases. We examined the effect of heat-inactivated Streptococcus pneumoniae R6 on MMP-2 and MMP-9 release by cultured aortic and brain capillary endothelial cells. Treatment with heat-inactivated S. pneumoniae caused an increased release of MMP-2 by both cell types.[1]

References

Regulation of matrix metalloproteinase expression in endothelial cells by heat-inactivated Streptococcus pneumoniae. Michel, U., Zobotke, R., Mäder, M., Nau, R. Infect. Immun. (2001) [Pubmed]

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