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Gene Review

MMP25  -  matrix metallopeptidase 25

Sus scrofa

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Disease relevance of MMP20


High impact information on MMP20


Chemical compound and disease context of MMP20


Biological context of MMP20


Anatomical context of MMP20


Associations of MMP20 with chemical compounds


Regulatory relationships of MMP20


Other interactions of MMP20


Analytical, diagnostic and therapeutic context of MMP20


  1. Matrix metalloproteinase inhibition during the development of congestive heart failure : effects on left ventricular dimensions and function. Spinale, F.G., Coker, M.L., Krombach, S.R., Mukherjee, R., Hallak, H., Houck, W.V., Clair, M.J., Kribbs, S.B., Johnson, L.L., Peterson, J.T., Zile, M.R. Circ. Res. (1999) [Pubmed]
  2. Selective inhibition of matrix metalloproteinase isozymes and in vivo protection against emphysema by substituted gamma-keto carboxylic acids. Ma, D., Jiang, Y., Chen, F., Gong, L.K., Ding, K., Xu, Y., Wang, R., Ge, A., Ren, J., Li, J., Li, J., Ye, Q. J. Med. Chem. (2006) [Pubmed]
  3. Regulation of matrix metalloproteinase expression in endothelial cells by heat-inactivated Streptococcus pneumoniae. Michel, U., Zobotke, R., Mäder, M., Nau, R. Infect. Immun. (2001) [Pubmed]
  4. Myocardial and interstitial matrix metalloproteinase activity after acute myocardial infarction in pigs. Etoh, T., Joffs, C., Deschamps, A.M., Davis, J., Dowdy, K., Hendrick, J., Baicu, S., Mukherjee, R., Manhaini, M., Spinale, F.G. Am. J. Physiol. Heart Circ. Physiol. (2001) [Pubmed]
  5. Matrix metalloproteinase inhibition reduces intimal hyperplasia in a porcine arteriovenous-graft model. Rotmans, J.I., Velema, E., Verhagen, H.J., Blankensteijn, J.D., de Kleijn, D.P., Stroes, E.S., Pasterkamp, G. J. Vasc. Surg. (2004) [Pubmed]
  6. Oral matrix metalloproteinase inhibition and arterial remodeling after balloon dilation: an intravascular ultrasound study in the pig. Sierevogel, M.J., Pasterkamp, G., Velema, E., de Jaegere, P.P., de Smet, B.J., Verheijen, J.H., de Kleijn, D.P., Borst, C. Circulation (2001) [Pubmed]
  7. Time-dependent changes in matrix metalloproteinase activity and expression during the progression of congestive heart failure: relation to ventricular and myocyte function. Spinale, F.G., Coker, M.L., Thomas, C.V., Walker, J.D., Mukherjee, R., Hebbar, L. Circ. Res. (1998) [Pubmed]
  8. Cruciate ligament laxity and femoral intercondylar notch narrowing in early-stage knee osteoarthritis. Quasnichka, H.L., Anderson-MacKenzie, J.M., Tarlton, J.F., Sims, T.J., Billingham, M.E., Bailey, A.J. Arthritis Rheum. (2005) [Pubmed]
  9. Generation and novel distribution of matrix metalloproteinase-derived aggrecan fragments in porcine cartilage explants. Fosang, A.J., Last, K., Stanton, H., Weeks, D.B., Campbell, I.K., Hardingham, T.E., Hembry, R.M. J. Biol. Chem. (2000) [Pubmed]
  10. Down-regulated expression of A disintegrin and metalloproteinase with thrombospondin-like repeats-1 by progesterone receptor antagonist is associated with impaired expansion of porcine cumulus-oocyte complexes. Shimada, M., Nishibori, M., Yamashita, Y., Ito, J., Mori, T., Richards, J.S. Endocrinology (2004) [Pubmed]
  11. Marimastat inhibits elastin degradation and matrix metalloproteinase 2 activity in a model of aneurysm disease. Treharne, G.D., Boyle, J.R., Goodall, S., Loftus, I.M., Bell, P.R., Thompson, M.M. The British journal of surgery. (1999) [Pubmed]
  12. Resuscitation with 100% O2 increases cerebral injury in hypoxemic piglets. Munkeby, B.H., Børke, W.B., Bjørnland, K., Sikkeland, L.I., Borge, G.I., Halvorsen, B., Saugstad, O.D. Pediatr. Res. (2004) [Pubmed]
  13. Matrix metalloproteinase and elastase activities in LPS-induced acute lung injury in guinea pigs. D'Ortho, M.P., Jarreau, P.H., Delacourt, C., Macquin-Mavier, I., Levame, M., Pezet, S., Harf, A., Lafuma, C. Am. J. Physiol. (1994) [Pubmed]
  14. Molecular cloning and mRNA tissue distribution of a novel matrix metalloproteinase isolated from porcine enamel organ. Bartlett, J.D., Simmer, J.P., Xue, J., Margolis, H.C., Moreno, E.C. Gene (1996) [Pubmed]
  15. Signaling pathways used in trabecular matrix metalloproteinase response to mechanical stretch. Bradley, J.M., Kelley, M.J., Rose, A., Acott, T.S. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  16. Angiotensin-converting enzyme and matrix metalloproteinase inhibition with developing heart failure: comparative effects on left ventricular function and geometry. McElmurray, J.H., Mukherjee, R., New, R.B., Sampson, A.C., King, M.K., Hendrick, J.W., Goldberg, A., Peterson, T.J., Hallak, H., Zile, M.R., Spinale, F.G. J. Pharmacol. Exp. Ther. (1999) [Pubmed]
  17. Weaning anorexia may contribute to local inflammation in the piglet small intestine. McCracken, B.A., Spurlock, M.E., Roos, M.A., Zuckermann, F.A., Gaskins, H.R. J. Nutr. (1999) [Pubmed]
  18. Keratinocyte growth factor stimulation of gelatinase (matrix metalloproteinase-9) and plasminogen activator in histiotypic epithelial cell culture. Putnins, E.E., Firth, J.D., Uitto, V.J. J. Invest. Dermatol. (1995) [Pubmed]
  19. Localization of bradykinin B(2) receptor in the follicles of porcine ovary and increased expression of matrix metalloproteinase-3 and -20 in cultured granulosa cells by bradykinin treatment. Kimura, A., Kihara, T., Ohkura, R., Ogiwara, K., Takahashi, T. Biol. Reprod. (2001) [Pubmed]
  20. Extracellular matrix collagen synthesis and degradation following coronary balloon angioplasty. Guarda, E., Katwa, L.C., Campbell, S.E., Tanner, M.A., Webel, R.M., Laughlin, H., Jenkins, S., Myers, P.R. J. Mol. Cell. Cardiol. (1996) [Pubmed]
  21. Altered hemodynamics controls matrix metalloproteinase activity and tenascin-C expression in neonatal pig lung. Jones, P.L., Chapados, R., Baldwin, H.S., Raff, G.W., Vitvitsky, E.V., Spray, T.L., Gaynor, J.W. Am. J. Physiol. Lung Cell Mol. Physiol. (2002) [Pubmed]
  22. Characterization of recombinant pig enamelysin activity and cleavage of recombinant pig and mouse amelogenins. Ryu, O.H., Fincham, A.G., Hu, C.C., Zhang, C., Qian, Q., Bartlett, J.D., Simmer, J.P. J. Dent. Res. (1999) [Pubmed]
  23. Tyrosine phosphatase inhibition induces loss of blood-brain barrier integrity by matrix metalloproteinase-dependent and -independent pathways. Lohmann, C., Krischke, M., Wegener, J., Galla, H.J. Brain Res. (2004) [Pubmed]
  24. Cardiac function, myocardial glutathione, and matrix metalloproteinase-2 levels in hypoxic newborn pigs reoxygenated by 21%, 50%, or 100% oxygen. Haase, E., Bigam, D.L., Nakonechny, Q.B., Rayner, D., Korbutt, G., Cheung, P.Y. Shock (2005) [Pubmed]
  25. ONO-4817, an orally active matrix metalloproteinase inhibitor, prevents lipopolysaccharide-induced proteoglycan release from the joint cartilage in guinea pigs. Yamada, A., Uegaki, A., Nakamura, T., Ogawa, K. Inflamm. Res. (2000) [Pubmed]
  26. Detection of changes in articular cartilage proteoglycan by T(1rho) magnetic resonance imaging. Wheaton, A.J., Dodge, G.R., Borthakur, A., Kneeland, J.B., Schumacher, H.R., Reddy, R. J. Orthop. Res. (2005) [Pubmed]
  27. Effect of doxycycline on sulfur mustard-induced respiratory lesions in guinea pigs. Guignabert, C., Taysse, L., Calvet, J.H., Planus, E., Delamanche, S., Galiacy, S., d'Ortho, M.P. Am. J. Physiol. Lung Cell Mol. Physiol. (2005) [Pubmed]
  28. Increased expression of matrix metalloproteinase-9 in neutrophils in glycogen-induced peritoneal inflammation of guinea pigs. Nagaoka, I., Hirota, S. Inflamm. Res. (2000) [Pubmed]
  29. Resuscitation of hypoxic piglets with 100% O2 increases pulmonary metalloproteinases and IL-8. Munkeby, B.H., Børke, W.B., Bjørnland, K., Sikkeland, L.I., Borge, G.I., Lømo, J., Rivera, S., Khrestchatisky, M., Halvorsen, B., Saugstad, O.D. Pediatr. Res. (2005) [Pubmed]
  30. Matrix metalloproteinase inhibitor prevents acute lung injury after cardiopulmonary bypass. Carney, D.E., Lutz, C.J., Picone, A.L., Gatto, L.A., Ramamurthy, N.S., Golub, L.M., Simon, S.R., Searles, B., Paskanik, A., Snyder, K., Finck, C., Schiller, H.J., Nieman, G.F. Circulation (1999) [Pubmed]
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