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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

An unexpected cause of muscle pain in diabetes.

Diabetic muscle infarction is a rare condition which may present to a rheumatologist. It was first reported in 1965. Two illustrative cases are described here and the mechanisms of pathogenesis discussed. Analysis of the published data, results of the muscle biopsies, and a technetium-99m sestamibi scan suggest that the condition, which occurs against a background of diabetic microangiopathy, can be triggered by an ischaemic event and causes extensive muscle necrosis through hypoxia-reperfusion injury and compartment syndrome.[1]


  1. An unexpected cause of muscle pain in diabetes. Silberstein, L., Britton, K.E., Marsh, F.P., Raftery, M.J., D'Cruz, D. Ann. Rheum. Dis. (2001) [Pubmed]
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