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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Back in the water: the return of the inositol phosphates.

Following the discovery of inositol-1,4,5-trisphosphate as a second messenger, many other inositol phosphates were discovered in quick succession, with some understanding of their synthesis pathways and a few guesses at their possible functions. But then it all seemed to go comparatively quiet, with an explosion of interest in the inositol lipids. Now the water-soluble phase is once again becoming a focus of interest. Old and new data point to a new vista of inositol phosphates, with functions in many diverse aspects of cell biology, such as ion-channel physiology, membrane dynamics and nuclear signalling.[1]

References

  1. Back in the water: the return of the inositol phosphates. Irvine, R.F., Schell, M.J. Nat. Rev. Mol. Cell Biol. (2001) [Pubmed]
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