- Oculocutaneous albinism types 1 and 3 are ER retention diseases: mutation of tyrosinase or Tyrp1 can affect the processing of both mutant and wild-type proteins. Toyofuku, K., Wada, I., Valencia, J.C., Kushimoto, T., Ferrans, V.J., Hearing, V.J. FASEB J. (2001)