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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

De novo production of (+)-aristolochene by sporulated surface cultures of Penicillium roqueforti.

The de novo production of the fungal metabolite, (+)-aristolochene by sporulated surface cultures of Penicillium roqueforti is reported for the first time. The biosynthesis of fungal volatiles by various sporulated surface cultures was monitored by solid phase micro-extraction (SPME). When comparing malt extract agar with sabouraud dextrose agar, the highest yield of the fungal metabolite (0.04 mg/ml of culture) was obtained with the latter medium. The biosynthesis of (+)-aristolochene showed a maximum during the fourth day after inoculation.[1]

References

  1. De novo production of (+)-aristolochene by sporulated surface cultures of Penicillium roqueforti. Demyttenaere, J.C., Adams, A., Van Belleghem, K., De Kimpe, N., König, W.A., Tkachev, A.V. Phytochemistry (2002) [Pubmed]
 
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