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Marinella, M.A.

Marinella,

Labetalol-induced hepatitis in a patient with chronic hepatitis B infection.

Drug-induced hepatotoxicity is an important cause of hepatocellular injury. Hepatic necrosis may range from asymptomatic elevations in transaminases to fulminant hepatic failure and death. A 50-year-old Asian man developed moderate elevations of hepatic transaminases after commencing labetalol therapy for a hypertensive cerebral hemorrhage. Extensive evaluation revealed evidence of chronic hepatitis B infection, of which the patient was previously not aware. Hepatic transaminases normalized after discontinuation of labetalol.[1]

References

Labetalol-induced hepatitis in a patient with chronic hepatitis B infection. Marinella, M.A. Journal of clinical hypertension (Greenwich, Conn.) (2002) [Pubmed]

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