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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Treatment of autonomic dysreflexia with phenoxybenzamine.

Our 9 patients with severe autonomic dysreflexia treated with phenoxybenzamine, an alpha-sympatholytic agent, had a dramatic relief of symptoms. Bladder and urethral pressure studies before and after treatment with this agent suggest that the inappropriate rise in urethral resistance in these patients is a result of an appropriate but extraordinary response to bladder filling.[1]


  1. Treatment of autonomic dysreflexia with phenoxybenzamine. McGuire, J., Wagner, F.M., Weiss, R.M. J. Urol. (1976) [Pubmed]
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