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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

The histone minority report: the variant shall not be silenced.

In this issue of Cell, Meneghini et al. demonstrate that replacement of canonical histone H2A with the histone variant H2A.Z within euchromatin prevents silent chromatin proteins from migrating into regions of the chromosome that normally are transcriptionally active. Thus, this highly conserved histone variant is critical for defining chromatin domains.[1]

References

  1. The histone minority report: the variant shall not be silenced. van Leeuwen, F., Gottschling, D.E. Cell (2003) [Pubmed]
 
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