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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Investigation of the early stages in soraphen A biosynthesis.

The unusual benzoate starter unit in soraphen A derives from phenylalanine via cinnamate in a beta-oxidative (plant-like) pathway; 3-phenyl-3-hydroxypropanoate incorporates directly into soraphen by loading onto module 2 of the PKS and indirectly from the beta-oxidative pathway to generate benzoyl CoA.[1]


  1. Investigation of the early stages in soraphen A biosynthesis. Hill, A.M., Thompson, B.L., Harris, J.P., Segret, R. Chem. Commun. (Camb.) (2003) [Pubmed]
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