Chemical Compound Review:
Soraphen A (1S,2S,3E,5R,6S,11S,14S,15R,16 R,17S,18S)...
Synonyms:
SureCN975745, CHEMBL1235782, CHEBI:45464, AC1NQZ96, 3jrx, ...
- A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes. Schupp, T., Toupet, C., Cluzel, B., Neff, S., Hill, S., Beck, J.J., Ligon, J.M. J. Bacteriol. (1995)
- Heterologous production of the antifungal polyketide antibiotic soraphen A of Sorangium cellulosum So ce26 in Streptomyces lividans. Zirkle, R., Ligon, J.M., Molnár, I. Microbiology (Reading, Engl.) (2004)
- A mechanism for the potent inhibition of eukaryotic acetyl-coenzyme A carboxylase by soraphen A, a macrocyclic polyketide natural product. Shen, Y., Volrath, S.L., Weatherly, S.C., Elich, T.D., Tong, L. Mol. Cell (2004)
- Inhibition of acetyl coenzyme A carboxylase activity restores expression of the INO1 gene in a snf1 mutant strain of Saccharomyces cerevisiae. Shirra, M.K., Patton-Vogt, J., Ulrich, A., Liuta-Tehlivets, O., Kohlwein, S.D., Henry, S.A., Arndt, K.M. Mol. Cell. Biol. (2001)
- The Saccharomyces cerevisiae hyperrecombination mutant hpr1Delta is synthetically lethal with two conditional alleles of the acetyl coenzyme A carboxylase gene and causes a defect in nuclear export of polyadenylated RNA. Schneiter, R., Guerra, C.E., Lampl, M., Gogg, G., Kohlwein, S.D., Klein, H.L. Mol. Cell. Biol. (1999)
- Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26. Ligon, J., Hill, S., Beck, J., Zirkle, R., Molnár, I., Zawodny, J., Money, S., Schupp, T. Gene (2002)
- A new dominant selection marker for transformation of Pichia pastoris to soraphen A resistance. Wan, H., Sjölinder, M., Schairer, H.U., Leclerque, A. J. Microbiol. Methods (2004)
- Identification of the yeast ACC1 gene product (acetyl-CoA carboxylase) as the target of the polyketide fungicide soraphen A. Vahlensieck, H.F., Pridzun, L., Reichenbach, H., Hinnen, A. Curr. Genet. (1994)
- Cloning, sequence analysis and disruption of the mglA gene involved in swarming motility of Sorangium cellulosum So ce26, a producer of the antifungal polyketide antibiotic soraphen A. Zirkle, R., Ligon, J.M., Molnár, I. J. Biosci. Bioeng. (2004)