Myoblasts fuse when loner meets ARF6.
Studies of myoblast fusion in Drosophila have revealed numerous signaling and structural proteins that regulate this critical event in muscle development. A paper by Chen et al. published in the September 19 issue of Cell adds ARF6, a GTPase, and one of its guanine nucleotide exchange factors to this set of players.[1]References
- Myoblasts fuse when loner meets ARF6. Donaldson, J.G. Dev. Cell (2003) [Pubmed]
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