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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Protease inhibitors reduce the reverse passive Arthus reaction.

Trasylol, ovomucoid, tranexamic acid and soybean inhibitor decrease the vascular permeability as measured by extravasation of 131I-albumin when injected with the antibody at induction of a reverse passive Arthus reaction in the rat skin. Trasylol given systemically also had a suppressive effect, similar to phenylbutazone. When the reaction was induced in the pleural cavity, both Trasylol and tranexamic acid reduced the influx of leucocytes.[1]

References

  1. Protease inhibitors reduce the reverse passive Arthus reaction. Hyman, Y.G., Vischer, T.L. Agents Actions (1978) [Pubmed]
 
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