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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Sculpting heart valves with NFATc and VEGF.

Heart valves are of vital importance for our moment-to-moment existence, but how they form remains a mystery. In this issue of Cell, Chang et al. reveal a novel role for calcineurin, NFATs, and VEGF in valve formation. Dynamic changes in NFAT/VEGF expression in regional myocardial and endocardial fields and developmental windows orchestrate this complex process.[1]


  1. Sculpting heart valves with NFATc and VEGF. Lambrechts, D., Carmeliet, P. Cell (2004) [Pubmed]
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