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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Viral immunity: cross-priming with the help of TLR3.

Cross-presentation is important for regulating T-cell responses to exogenous antigens and can maintain tolerance (cross-tolerance) or induce immune responses (cross-priming). Recent exciting results on the role of the Toll-like receptor TLR3 in promoting cross-priming of viral antigens provide new insights into the mechanisms that allow Toll-like receptor signaling to bridge innate and adaptive immune responses.[1]

References

  1. Viral immunity: cross-priming with the help of TLR3. Salio, M., Cerundolo, V. Curr. Biol. (2005) [Pubmed]
 
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