Mantovani,
Cardell,
D'amico,
Basler,
Kazura,
Polentarutti,
Daehnel,
Pearlman,
Adner,
Allavena,
Cho,
Stoppacciaro,
Mancinelli,
Bosisio,
van't Veer,
Gillette-Ferguson,
McGarry,
Muzio,
Golenbock,
Ruco,
Penton-Rol,
Taylor,
Cardenas,
Hise,
Shaw,
Kotaro Fukuda,
Tomoya Watanabe,
Takashi Tokisue,
Tadayuki Tsujita,
Satoshi Nishikawa,
Tsunemi Hasegawa,
Tsukasa Seya,
Misako Matsumoto,
Zamarin,
Mansson,
Fitzgerald,
Palese,
- Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus. Guillot, L., Le Goffic, R., Bloch, S., Escriou, N., Akira, S., Chignard, M., Si-Tahar, M. J. Biol. Chem. (2005)
- Human Langerhans Cells Express a Specific TLR Profile and Differentially Respond to Viruses and Gram-Positive Bacteria. Flacher, V., Bouschbacher, M., Verron??se, E., Massacrier, C., Sisirak, V., Berthier-Vergnes, O., de Saint-Vis, B., Caux, C., Dezutter-Dambuyant, C., Lebecque, S., Valladeau, J. J. Immunol. (2006)
- Innate Immune Responses to Endosymbiotic Wolbachia Bacteria in Brugia malayi and Onchocerca volvulus Are Dependent on TLR2, TLR6, MyD88, and Mal, but Not TLR4, TRIF, or TRAM. Hise, A.G., Daehnel, K., Gillette-Ferguson, I., Cho, E., McGarry, H.F., Taylor, M.J., Golenbock, D.T., Fitzgerald, K.A., Kazura, J.W., Pearlman, E. J. Immunol. (2007)
- Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis. Harii, N., Lewis, C.J., Vasko, V., McCall, K., Benavides-Peralta, U., Sun, X., Ringel, M.D., Saji, M., Giuliani, C., Napolitano, G., Goetz, D.J., Kohn, L.D. Mol. Endocrinol. (2005)
- Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Cario, E., Podolsky, D.K. Infect. Immun. (2000)
- Expression of Toll-like receptor 3 in the human cerebellar cortex in rabies, herpes simplex encephalitis, and other neurological diseases. Jackson, A.C., Rossiter, J.P., Lafon, M. J. Neurovirol. (2006)
- Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Alexopoulou, L., Holt, A.C., Medzhitov, R., Flavell, R.A. Nature (2001)
- CD14: chaperone or matchmaker? Finberg, R.W., Kurt-Jones, E.A. Immunity (2006)
- Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses. Yang, K., Puel, A., Zhang, S., Eidenschenk, C., Ku, C.L., Casrouge, A., Picard, C., von Bernuth, H., Senechal, B., Plancoulaine, S., Al-Hajjar, S., Al-Ghonaium, A., Maródi, L., Davidson, D., Speert, D., Roifman, C., Garty, B.Z., Ozinsky, A., Barrat, F.J., Coffman, R.L., Miller, R.L., Li, X., Lebon, P., Rodriguez-Gallego, C., Chapel, H., Geissmann, F., Jouanguy, E., Casanova, J.L. Immunity (2005)
- TLR ignores methylated RNA? Ishii, K.J., Akira, S. Immunity (2005)
- Cutting Edge: TLR3 Stimulation Suppresses Experimental Autoimmune Encephalomyelitis by Inducing Endogenous IFN-beta. Touil, T., Fitzgerald, D., Zhang, G.X., Rostami, A., Gran, B. J. Immunol. (2006)
- p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells. Pisegna, S., Pirozzi, G., Piccoli, M., Frati, L., Santoni, A., Palmieri, G. Blood (2004)
- Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4. Doyle, S.E., O'Connell, R., Vaidya, S.A., Chow, E.K., Yee, K., Cheng, G. J. Immunol. (2003)
- Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cells. Liu, P., Jamaluddin, M., Li, K., Garofalo, R.P., Casola, A., Brasier, A.R. J. Virol. (2007)
- Identification of soluble CD14 as an endogenous agonist for Toll-like receptor 2 on human astrocytes by genome-scale functional screening of glial cell derived proteins. Bsibsi, M., Bajramovic, J.J., Van Duijvenvoorden, E., Persoon, C., Ravid, R., Van Noort, J.M., Vogt, M.H. Glia (2007)
- Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation. Hausmann, M., Kiessling, S., Mestermann, S., Webb, G., Spöttl, T., Andus, T., Schölmerich, J., Herfarth, H., Ray, K., Falk, W., Rogler, G. Gastroenterology (2002)
- Toll-like receptors stimulate human neutrophil function. Hayashi, F., Means, T.K., Luster, A.D. Blood (2003)
- TLR signaling tailors innate immune responses in human microglia and astrocytes. Jack, C.S., Arbour, N., Manusow, J., Montgrain, V., Blain, M., McCrea, E., Shapiro, A., Antel, J.P. J. Immunol. (2005)
- An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors. Pinhal-Enfield, G., Ramanathan, M., Hasko, G., Vogel, S.N., Salzman, A.L., Boons, G.J., Leibovich, S.J. Am. J. Pathol. (2003)
- Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kappa B activation and IFN-beta synthesis downstream of Toll-like receptor 3 and 4. Aksoy, E., Vanden Berghe, W., Detienne, S., Amraoui, Z., Fitzgerald, K.A., Haegeman, G., Goldman, M., Willems, F. Eur. J. Immunol. (2005)
- Modulation of expression and function of Toll-like receptor 3 in A549 and H292 cells by histamine. Hou, Y.F., Zhou, Y.C., Zheng, X.X., Wang, H.Y., Fu, Y.L., Fang, Z.M., He, S.H. Mol. Immunol. (2006)
- Interferon-beta induction through toll-like receptor 3 depends on double-stranded RNA structure. Okahira, S., Nishikawa, F., Nishikawa, S., Akazawa, T., Seya, T., Matsumoto, M. DNA Cell Biol. (2005)
- Toll-like receptor 3 agonist enhances IFN-gamma and TNF-alpha production by murine uterine NK cells. Zhang, J., Sun, R., Wei, H., Wu, D., Tian, Z. Int. Immunopharmacol. (2007)
- Key differences in TLR3/poly I:C signaling and cytokine induction by human primary cells: a phenomenon absent from murine cell systems. Lundberg, A.M., Drexler, S.K., Monaco, C., Williams, L.M., Sacre, S.M., Feldmann, M., Foxwell, B.M. Blood (2007)
- Modulation of double-stranded RNA recognition by the N-terminal histidine-rich region of the human toll-like receptor 3. Fukuda, K., Watanabe, T., Tokisue, T., Tsujita, T., Nishikawa, S., Hasegawa, T., Seya, T., Matsumoto, M. J. Biol. Chem. (2008)
- TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements. Nishiya, T., Kajita, E., Miwa, S., Defranco, A.L. J. Biol. Chem. (2005)
- Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. Muzio, M., Bosisio, D., Polentarutti, N., D'amico, G., Stoppacciaro, A., Mancinelli, R., van't Veer, C., Penton-Rol, G., Ruco, L.P., Allavena, P., Mantovani, A. J. Immunol. (2000)
- Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. Yamamoto, M., Sato, S., Mori, K., Hoshino, K., Takeuchi, O., Takeda, K., Akira, S. J. Immunol. (2002)
- SOCS1-negative feedback of STAT1 activation is a key pathway in the dsRNA-induced innate immune response of human keratinocytes. Dai, X., Sayama, K., Yamasaki, K., Tohyama, M., Shirakata, Y., Hanakawa, Y., Tokumaru, S., Yahata, Y., Yang, L., Yoshimura, A., Hashimoto, K. J. Invest. Dermatol. (2006)
- IFN-alpha enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression. Tissari, J., Sirén, J., Meri, S., Julkunen, I., Matikainen, S. J. Immunol. (2005)
- IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Doyle, S., Vaidya, S., O'Connell, R., Dadgostar, H., Dempsey, P., Wu, T., Rao, G., Sun, R., Haberland, M., Modlin, R., Cheng, G. Immunity (2002)
- Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways. Shaw, M.L., Cardenas, W.B., Zamarin, D., Palese, P., Basler, C.F. J. Virol. (2005)
- TLR ligands and cytokines induce CXCR3 ligands in endothelial cells: enhanced CXCL9 in autoimmune arthritis. Loos, T., Dekeyzer, L., Struyf, S., Schutyser, E., Gijsbers, K., Gouwy, M., Fraeyman, A., Put, W., Ronsse, I., Grillet, B., Opdenakker, G., Damme, J.V., Proost, P. Lab. Invest. (2006)
- Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9. Lebre, M.C., van der Aar, A.M., van Baarsen, L., van Capel, T.M., Schuitemaker, J.H., Kapsenberg, M.L., de Jong, E.C. J. Invest. Dermatol. (2007)
- Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis. Mansson, A., Adner, M., Cardell, L.O. Respir. Res. (2006)
- Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation. Goriely, S., Molle, C., Nguyen, M., Albarani, V., Haddou, N.O., Lin, R., De Wit, D., Flamand, V., Willems, F., Goldman, M. Blood (2006)