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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Anti-angiogenic activity of basic-type, selective cyclooxygenase (COX)-1 inhibitors.

Indole- and indoline-type basic COX-1-selective competitive inhibitors, 5-amino-1-(3,5-dimethylbenzoyl)-1H-indole (1) and 5-amino-1-(3,5-dimethylphenyl)-2,3-dihydro-1H-indole (2), were found to possess anti-angiogenic activity estimated as a tube formation-inhibition using human umbilical vein endothelial cells (HUVECs).[1]

References

  1. Anti-angiogenic activity of basic-type, selective cyclooxygenase (COX)-1 inhibitors. Sano, H., Noguchi, T., Miyajima, A., Hashimoto, Y., Miyachi, H. Bioorg. Med. Chem. Lett. (2006) [Pubmed]
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