- Spatial conformation and topography of the tyrosine aromatic ring in substrate recognition by protein tyrosine kinases. Ruzza, P., Cesaro, L., Tourwé, D., Calderan, A., Biondi, B., Maes, V., Menegazzo, I., Osler, A., Rubini, C., Guiotto, A., Pinna, L.A., Borin, G., Donella-Deana, A. J. Med. Chem. (2006)