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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: Preparation of FXR and PPAR ligands.

Novel, potent farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor alpha (PPARalpha) agonists were obtained by using a diphenylmethane skeleton as a substitute for a steroid skeleton.[1]

References

  1. Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: Preparation of FXR and PPAR ligands. Kainuma, M., Kasuga, J., Hosoda, S., Wakabayashi, K., Tanatani, A., Nagasawa, K., Miyachi, H., Makishima, M., Hashimoto, Y. Bioorg. Med. Chem. Lett. (2006) [Pubmed]
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