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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Susceptibilities of Propionibacterium acnes Ophthalmic Isolates to Ertapenem, Meropenem, and Cefepime.

We investigated the in vitro susceptibilities of 23 Propionibacterium acnes ophthalmic isolates to ertapenem, meropenem, and cefepime by utilizing the Etest. The MICs ranged from 0.094 mug/ml to 0.75 mug/ml, 0.094 mug/ml to 1.5 mug/ml, and 1 mug/ml to 12 mug/ml for ertapenem, meropenem, and cefepime, respectively. Based on our excellent in vitro carbapenem susceptibility results, in vivo studies using ertapenem and meropenem in a rabbit model of P. acnes endophthalmitis are warranted.[1]

References

  1. Susceptibilities of Propionibacterium acnes Ophthalmic Isolates to Ertapenem, Meropenem, and Cefepime. Shames, R., Satti, F., Vellozzi, E.M., Smith, M.A. J. Clin. Microbiol. (2006) [Pubmed]
 
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