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An easy route towards regioselectively difunctionalized cyclens and new cryptands.

Reductive amination of various aldehydes with cyclen represents a very convenient method for the synthesis of a wide range of 1,7-difunctionalized cyclens, as well as new cryptands.[1]

References

  1. An easy route towards regioselectively difunctionalized cyclens and new cryptands. Chaux, F., Denat, F., Espinosa, E., Guilard, R. Chem. Commun. (Camb.) (2006) [Pubmed]
 
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