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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Building addressable libraries: the use of a mass spectrometry cleavable linker for monitoring reactions on a microelectrode array.

Time-of-flight secondary ion mass spectrometry ( TOF SIMS) has been used in conjunction with a mass spectrometry cleavable linker to determine the percent conversion of reactions that were conducted site-selectively on an addressable microelectrode array. When combined with fluorescence techniques for analysis of the reactions, the TOF SIMS experiment provides a means for optimization of both reaction confinement and reaction efficiency on the microelectrode arrays.[1]

References

  1. Building addressable libraries: the use of a mass spectrometry cleavable linker for monitoring reactions on a microelectrode array. Chen, C., Nagy, G., Walker, A.V., Maurer, K., McShea, A., Moeller, K.D. J. Am. Chem. Soc. (2006) [Pubmed]
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