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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

A neural protection racket: AMPK and the GABA(B) receptor.

The cellular energy-sensing kinase AMPK is known to be activated in neurons in response to metabolic insults, but the downstream consequences have been unclear. A study by Kuramoto and colleagues in this issue of Neuron favors the idea that AMPK activation is neuroprotective, and suggests a potential mechanism for this effect involving phosphorylation of the GABA(B) receptor.[1]

References

  1. A neural protection racket: AMPK and the GABA(B) receptor. Hardie, D.G., Frenguelli, B.G. Neuron (2007) [Pubmed]
 
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