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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Nitrofurantoin neuropathy: a forgotten adverse effect.

BACKGROUND: Nitrofurantoin is a widely prescribed antibiotic used to treat uncomplicated lower urinary tract infections. Unknown in the obstetric and gynecologic literature is the complication of peripheral neuropathy as an adverse effect. CASE: We describe a patient who developed a severe sensory neuropathy after taking nitrofurantoin intermittently and then continuously over a 7-year period. She recovered almost completely after its discontinuation. CONCLUSION: Peripheral neuropathy is a rare and potentially reversible adverse effect, unreported in the obstetric and gynecologic literature, and commonly unrecognized by physicians who prescribe it.[1]

References

  1. Nitrofurantoin neuropathy: a forgotten adverse effect. Kammire, L.D., Donofrio, P.D. Obstet. Gynecol (2007) [Pubmed]
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