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MeSH Review

Peripheral Nervous System Diseases

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Disease relevance of Peripheral Nervous System Diseases


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Chemical compound and disease context of Peripheral Nervous System Diseases


Biological context of Peripheral Nervous System Diseases


Anatomical context of Peripheral Nervous System Diseases


Gene context of Peripheral Nervous System Diseases


Analytical, diagnostic and therapeutic context of Peripheral Nervous System Diseases


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  11. The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum. Howard, H.C., Mount, D.B., Rochefort, D., Byun, N., Dupré, N., Lu, J., Fan, X., Song, L., Rivière, J.B., Prévost, C., Horst, J., Simonati, A., Lemcke, B., Welch, R., England, R., Zhan, F.Q., Mercado, A., Siesser, W.B., George, A.L., McDonald, M.P., Bouchard, J.P., Mathieu, J., Delpire, E., Rouleau, G.A. Nat. Genet. (2002) [Pubmed]
  12. Ganglioside-induced differentiation-associated protein-1 is mutant in Charcot-Marie-Tooth disease type 4A/8q21. Baxter, R.V., Ben Othmane, K., Rochelle, J.M., Stajich, J.E., Hulette, C., Dew-Knight, S., Hentati, F., Ben Hamida, M., Bel, S., Stenger, J.E., Gilbert, J.R., Pericak-Vance, M.A., Vance, J.M. Nat. Genet. (2002) [Pubmed]
  13. Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies. Martini, R., Zielasek, J., Toyka, K.V., Giese, K.P., Schachner, M. Nat. Genet. (1995) [Pubmed]
  14. Charcot-Marie-Tooth disease type 1A. Association with a spontaneous point mutation in the PMP22 gene. Roa, B.B., Garcia, C.A., Suter, U., Kulpa, D.A., Wise, C.A., Mueller, J., Welcher, A.A., Snipes, G.J., Shooter, E.M., Patel, P.I., Lupski, J.R. N. Engl. J. Med. (1993) [Pubmed]
  15. Lack of tocopherol in peripheral nerves of vitamin E-deficient patients with peripheral neuropathy. Traber, M.G., Sokol, R.J., Ringel, S.P., Neville, H.E., Thellman, C.A., Kayden, H.J. N. Engl. J. Med. (1987) [Pubmed]
  16. Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial. Backonja, M., Beydoun, A., Edwards, K.R., Schwartz, S.L., Fonseca, V., Hes, M., LaMoreaux, L., Garofalo, E. JAMA (1998) [Pubmed]
  17. Acupuncture and amitriptyline for pain due to HIV-related peripheral neuropathy: a randomized controlled trial. Terry Beirn Community Programs for Clinical Research on AIDS. Shlay, J.C., Chaloner, K., Max, M.B., Flaws, B., Reichelderfer, P., Wentworth, D., Hillman, S., Brizz, B., Cohn, D.L. JAMA (1998) [Pubmed]
  18. Peripheral diabetic neuropathy treated with amitriptyline and fluphenazine. Davis, J.L., Lewis, S.B., Gerich, J.E., Kaplan, R.A., Schultz, T.A., Wallin, J.D. JAMA (1977) [Pubmed]
  19. A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101. Baldwin, R.M., Owzar, K., Zembutsu, H., Chhibber, A., Kubo, M., Jiang, C., Watson, D., Eclov, R.J., Mefford, J., McLeod, H.L., Friedman, P.N., Hudis, C.A., Winer, E.P., Jorgenson, E.M., Witte, J.S., Shulman, L.N., Nakamura, Y., Ratain, M.J., Kroetz, D.L. Clin. Cancer Res. (2012) [Pubmed]
  20. Gene dosage is a mechanism for Charcot-Marie-Tooth disease type 1A. Lupski, J.R., Wise, C.A., Kuwano, A., Pentao, L., Parke, J.T., Glaze, D.G., Ledbetter, D.H., Greenberg, F., Patel, P.I. Nat. Genet. (1992) [Pubmed]
  21. Apoptotic phenotype induced by overexpression of wild-type gas3/PMP22: its relation to the demyelinating peripheral neuropathy CMT1A. Fabbretti, E., Edomi, P., Brancolini, C., Schneider, C. Genes Dev. (1995) [Pubmed]
  22. Peripheral myelin protein 22 is a constituent of intercellular junctions in epithelia. Notterpek, L., Roux, K.J., Amici, S.A., Yazdanpour, A., Rahner, C., Fletcher, B.S. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  23. Curcumin treatment abrogates endoplasmic reticulum retention and aggregation-induced apoptosis associated with neuropathy-causing myelin protein zero-truncating mutants. Khajavi, M., Inoue, K., Wiszniewski, W., Ohyama, T., Snipes, G.J., Lupski, J.R. Am. J. Hum. Genet. (2005) [Pubmed]
  24. Exposure at the cell surface is required for gas3/PMP22 To regulate both cell death and cell spreading: implication for the Charcot-Marie-Tooth type 1A and Dejerine-Sottas diseases. Brancolini, C., Edomi, P., Marzinotto, S., Schneider, C. Mol. Biol. Cell (2000) [Pubmed]
  25. Misonidazole Neuropathy: a clinical, electrophysiological, and histological study. Melgaard, B., Hansen, H.S., Kamieniecka, Z., Paulson, O.B., Pedersen, A.G., Tang, X., Trojaborg, W. Ann. Neurol. (1982) [Pubmed]
  26. Immunoreactive myelin basic protein in cerebrospinal fluid of patients with peripheral neuropathies. Cornblath, D.R., Griffin, J.W., Tennekoon, G.I. Ann. Neurol. (1986) [Pubmed]
  27. Generation of human B-cell hybridomas secreting monoclonal anti-myelin-associated glycoprotein antibodies from a patient with neuropathy. Spatz, L., Lieberson, B., Abraham, J., Miller, O.J., Miller, D.A., Latov, N. Ann. Neurol. (1987) [Pubmed]
  28. Decreased myo-inositol content and Na+-K+-ATPase activity in superior cervical ganglion of STZ-diabetic rat and prevention by aldose reductase inhibition. Greene, D.A., Mackway, A.M. Diabetes (1986) [Pubmed]
  29. Detection and processing of peripheral myelin protein PMP22 in cultured Schwann cells. Pareek, S., Suter, U., Snipes, G.J., Welcher, A.A., Shooter, E.M., Murphy, R.A. J. Biol. Chem. (1993) [Pubmed]
  30. Nab proteins are essential for peripheral nervous system myelination. Le, N., Nagarajan, R., Wang, J.Y., Svaren, J., LaPash, C., Araki, T., Schmidt, R.E., Milbrandt, J. Nat. Neurosci. (2005) [Pubmed]
  31. Functional consequences of mutations in the early growth response 2 gene (EGR2) correlate with severity of human myelinopathies. Warner, L.E., Svaren, J., Milbrandt, J., Lupski, J.R. Hum. Mol. Genet. (1999) [Pubmed]
  32. Connexin 31 (GJB3) is expressed in the peripheral and auditory nerves and causes neuropathy and hearing impairment. López-Bigas, N., Olivé, M., Rabionet, R., Ben-David, O., Martínez-Matos, J.A., Bravo, O., Banchs, I., Volpini, V., Gasparini, P., Avraham, K.B., Ferrer, I., Arbonés, M.L., Estivill, X. Hum. Mol. Genet. (2001) [Pubmed]
  33. Schwann cell expression of PLP1 but not DM20 is necessary to prevent neuropathy. Shy, M.E., Hobson, G., Jain, M., Boespflug-Tanguy, O., Garbern, J., Sperle, K., Li, W., Gow, A., Rodriguez, D., Bertini, E., Mancias, P., Krajewski, K., Lewis, R., Kamholz, J. Ann. Neurol. (2003) [Pubmed]
  34. Hypogonadotropic hypogonadism and peripheral neuropathy in Ebf2-null mice. Corradi, A., Croci, L., Broccoli, V., Zecchini, S., Previtali, S., Wurst, W., Amadio, S., Maggi, R., Quattrini, A., Consalez, G.G. Development (2003) [Pubmed]
  35. A trial of amitriptyline and fluphenazine in the treatment of painful diabetic neuropathy. Mendel, C.M., Klein, R.F., Chappell, D.A., Dere, W.H., Gertz, B.J., Karam, J.H., Lavin, T.N., Grunfeld, C. JAMA (1986) [Pubmed]
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  38. Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas. Fine, H.A., Figg, W.D., Jaeckle, K., Wen, P.Y., Kyritsis, A.P., Loeffler, J.S., Levin, V.A., Black, P.M., Kaplan, R., Pluda, J.M., Yung, W.K. J. Clin. Oncol. (2000) [Pubmed]
  39. Degeneration in central and peripheral nervous systems produced by pure n-hexane: an experimental study. Schaumburg, H.H., Spencer, P.S. Brain (1976) [Pubmed]
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