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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Antineoplastic agents. 558. Ampelocissus sp. cancer cell growth inhibitory constituents.

An investigation of the Phillippine Ampelocissus sp. roots for cancer cell growth inhibitory components led to the isolation of a new acetogenin characterized as 22-epicalamistrin (1) employing primarily 2D NMR and high-resolution mass spectral analysis. Two other antineoplastic constituents proved to be the known acetogenin uvaribonin (2) and chalcone 3. Constituents 1-3 were all found to show significant cancer cell growth inhibitory activity against a panel of human cancer cell lines.[1]

References

  1. Antineoplastic agents. 558. Ampelocissus sp. cancer cell growth inhibitory constituents. Pettit, G.R., Mukku, V.J., Cragg, G., Herald, D.L., Knight, J.C., Herald, C.L., Chapuis, J.C. J. Nat. Prod. (2008) [Pubmed]
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