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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The initiation region of the SV40 VP1 gene.

The sequence of 15 nucleotides located at the 5' terminus of the plus strand of the SV40 Hind K fragment has been determined as (5') A-G-C-T-T-A-T-G-A-A-G-A-T-G-G (3'). The 3' on OH terminal G of this segment is part of the G-C-C codeword for the N terminal alanine of the VP1 protein. This region therefore presumably corresponds to a ribosome binding site on the 16S late mRNA. Complementarily to the 3' OH of eucaryotic 18S ribosomal RNA and homology with the BMV coat ribosome binding site are discussed.[1]


  1. The initiation region of the SV40 VP1 gene. Van de Voorde, A., Contreras, R., Rogiers, R., Fiers, W. Cell (1976) [Pubmed]
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