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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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C1R subcomponent polymorphism in Japanese: description of a new allele.

The polymorphism of C1R was investigated in 570 unrelated Japanese individuals using isoelectric focusing and immunoblotting. A total of 11 different C1R phenotypes including a new pattern designated C1R 11-1 were observed. The allele frequencies were C1R*1 = 0.4561, C1R*2 = 0.3377, C1R*5 = 0.1956, C1R*8 = 0.0088 and C1R*R (C1R*9 and C1R*11) = 0.0018. The population data fitted the Hardy-Weinberg equilibrium. The C1R polymorphism in Japanese was shown to be controlled by 3 common alleles, C1R*1, C1R*2 and C1R*5, as compared to Caucasians where only the former 2 are present commonly. This complement system can be a useful genetic marker for anthropological studies.[1]

References

  1. C1R subcomponent polymorphism in Japanese: description of a new allele. Kido, A., Komatsu, N., Kimura, Y., Oya, M. Hum. Hered. (1991) [Pubmed]
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