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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Inhibition of mitochondrial fragmentation during sake brewing causes high malate production in sake yeast.

We previously demonstrated the presence and fragmentation of mitochondria during alcohol fermentation. Here, we show that Fis1p induces mitochondrial fragmentation, and inhibition of mitochondrial fragmentation causes higher malate production during sake brewing. These findings indicate that mitochondrial morphology affects the metabolism of constituents, providing a breeding strategy for high-malate-producing yeasts.[1]

References

  1. Inhibition of mitochondrial fragmentation during sake brewing causes high malate production in sake yeast. Kitagaki, H., Kato, T., Isogai, A., Mikami, S., Shimoi, H. J. Biosci. Bioeng. (2008) [Pubmed]
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