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Disease relevance of Mitochondria


Psychiatry related information on Mitochondria


High impact information on Mitochondria

  • The amplitude and dynamics of the Ca(2+) signal are shaped by several mechanisms, including K(+) channels and membrane potential, slow modulation of the plasma membrane Ca(2+)-ATPase, and mitochondria that buffer Ca(2+) and prevent the inactivation of CRAC channels [11].
  • Passive lymphokine withdrawal death may result from the cytoplasmic activation of caspases that is regulated by mitochondria and the Bcl-2 protein [12].
  • DNA polymerase (pol) gamma is the sole DNA polymerase in animal mitochondria [13].
  • Most forms of RNase P are ribonucleoproteins, i.e., they consist of an essential RNA subunit and protein subunits, although the composition of the enzyme in mitochondria and chloroplasts is still under debate [14].
  • The role of the various lipid-binding proteins in transmembrane and cytosolic transport of lipids is considered as well as regulation of lipid entry into the mitochondria, focusing on the putative role of AMP-activated protein kinase (AMPK), acetyl CoA carboxylase (ACC), and carnitine during exercise [15].

Chemical compound and disease context of Mitochondria


Biological context of Mitochondria


Anatomical context of Mitochondria


Associations of Mitochondria with chemical compounds


Gene context of Mitochondria


Analytical, diagnostic and therapeutic context of Mitochondria


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  35. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Luo, X., Budihardjo, I., Zou, H., Slaughter, C., Wang, X. Cell (1998) [Pubmed]
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