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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

A monolithic photonic microcantilever device for in situ monitoring of volatile compounds.

A monolithic photonic microcantilever device is presented comprising silicon light sources and detectors self-aligned to suspended silicon nitride waveguides all integrated into the same silicon chip. A silicon nitride waveguide optically links a silicon light emitting diode to a detector. Then, the optocoupler releases a localized formation of resist-silicon nitride cantilevers through e-beam lithography, dry etching and precisely controlled wet etching through a special microfluidic set-up. Fine micro-optical sensing functions are performed without the need for any off-chip optics. As the bimaterial microcantilevers are deflected by the stressed polymer film, the disrupted waveguide acts like a photonic switch. Cantilever deflections in the order of 1 A caused by thickness variations in the order of 0.005 A are detectable following changes in the physicochemical factors affecting the polymer film thickness. Such factors include the sorption of volatile compounds and through a proper set-up the response to certain vapor concentrations is monitored in real time.[1]


  1. A monolithic photonic microcantilever device for in situ monitoring of volatile compounds. Misiakos, K., Raptis, I., Gerardino, A., Contopanagos, H., Kitsara, M. Lab. Chip (2009) [Pubmed]
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